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10.3390/tropicalmed7040054 23 CupolilloE.CavalcantiA

Moreover, certain HMs are recognized as human carcinogens, producing reactive oxygen species (ROS), which impair host defense mechanisms, causing genomic instability, and can lead to cancer [35]

Acetaminophens Complementary Analgesic Mechanism Acetaminophen inhibits cyclooxygenase (COX) enzyme activity in the central nervous system, reducing prostaglandin E2 synthesis and producing analgesia and antipyresis through pathways that do not involve opioid receptor binding