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Am J Physiol Cell Physiol 294:13051312

Potentiation of insulin signaling contributes to heart failure in type 2 diabetes: a hypothesis supported by both mechanistic studies and clinical trials

MSC-EVs function predominantly by the activation of autophagy via the catalase enzyme, the Nrf2 signalling pathway, the miR 146a-inhibited NF-B pathway, and the targeting of the PTEN-PI3 K/Akt pathway by miR-223 (145)