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We have observed that, with increasing gate time, \(\beta \) gradually decreases and ACF gets noisier which is in accordance with the previous findings 12,13

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To address this possibility, in a number of animal 118,119 and human studies, 120 high doses of anti-catabolic glucocorticoids, which inhibit the activation of MMPs 121 and the expression inflammatory cytokines, 122 have been administered