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ATX code V03AB32 Indications for use - prevention of neurotoxicity during chemotherapy with cisplatin or other related compounds List of information required before use Contraindications - hypersensitivity to the active substances or to any of the excipients Necessary precautions for use In case of adverse reactions during intravenous administration, use of the drug should be discontinued immediately

doi: 10.1093/oxfordjournals.aje.a112404 57 HillerRSperdutoRDEdererF

Although these mechanisms have been predominantly characterized in non-tumor systems, they provide important conceptual frameworks for understanding the directionality and execution of mitochondrial transfer under metabolic stress

Challenges that can be anticipated in future research studies include designing studies that will help elicit causality