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Kensler TW, Roebuck BD, Wogan GN, Groopman JD (2011) Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology

Mechanistically, TLR2 activation induces changes in glucose metabolism-related enzymes within CD4 + T cells, leading to a shift in glucose flux towards the PPP (18)

A comparison of normal GSH level with the IC 50 of cisplatin for each cell line did not reveal any kind of correlation, to conclude that intracellular amount of GSH might be the critical index for the cell line resistance to this drug