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While enhancing neurological recovery, cognitive function, and quality of life after stroke is increasingly recognized as equally-if not more important-in many clinical and personal contexts than prevention alone

The CP is initiated by C1q binding to antigen-antibody complexes, thereby inducing a cascade via C2 and C4 cleavage, leading to the production of CP C3 convertase (C4b2b)

Fibrinogen-Mimetic Nanoplatforms: Platelet-activatable nanoparticles (e.g., RGD-Chi@tPA) enhance thrombus targeting and tissue plasminogen activator penetration for efficient thrombolysis [110](Figure 6)

By sensing tissue lactate, synovial T cells lose their mobility and are trapped in the tissue niche