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Considerations for Therapeutic Applications [0600] A consideration in genome editing therapy is the choice of sequence-specific nuclease, such as a variant of a Cas nuclease

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Metabolic and Molecular Effects of Exercise on Oestrogen in Skeletal Muscle Oestrogens are steroid hormones, primarily produced in the ovaries from testosterone via an aromatase enzyme, of which women have four times the amount compared with men, until the menopause (Hansen and Kjaer, 2014)

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