slc25a39 is necessary for mitochondrial glutathione import in mammalian cells

slc25a39 is necessary for mitochondrial glutathione import in mammalian cells protein levels are directly regulated by cellular GSH Mitochondrial GSH import is mediated

Name: slc25a39 is necessary for mitochondrial glutathione import in mammalian cells protein levels are directly regulated by cellular GSH Mitochondrial GSH import is mediated
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Mitochondrial GSH import is mediated by SLC25A39 a, Volcano plots Download Scientific Diagram Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS Nature Communications Slc25a39 and Slc25a40 Expression in Mice with Bile Duct Ligation or Lipopolysaccharide Treatment Autoregulatory control of mitochondrial glutathione homeostasis Science

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The hypothesis has expanded to include vascular dysfunction, oxidative stress, microglial activation, and impaired proteolysis (Roda et al., 2022)

Occurrence Moreover, glutathione occurs in raw meat, fruit, and vegetables, while glutamine occurs in beef, pork, dairy products, raw spinach, raw parsley, and cabbage