DSPC usually inhibits membrane fusion with the endosomal membrane, thus inhibiting endosomal escape, whereas DOPE, with unsaturated hydrophobic tails, can undergo a phase transition to an inverted hexagonal (H II ) phase, thus facilitating membrane fusion-mediated endosomal escape

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The glutamate scavanging is achieved by lowering glutamate levels in the blood by intravenous injection of the blood enzyme glutamate oxaloacetate transaminase (GOT)
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