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Characterization of the human Omega class glutathione transferase genes and associated polymorphisms

Reducing oxidative stress caused by working out is important for people who work out often and those who do not

Lancet (Lond., Engl.) 389 , 5666 (2017)

It was recently shown that pemetrexed may play a role in cisplatin resistance in lung cancer by increasing the expression of Orai3 calcium channels as well as the expression of certain ABC transporters like MDR1 and MRP-5 responsible for cisplatin efflux and therefore a reduction of the effect of cisplatin [16] As current therapies are based on the co-administration of pemetrexed and cisplatin, there may be interactions between pemetrexed and cisplatin, including a reduction in the therapeutic effects of cisplatin caused by pemetrexed