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K., Frolova, A

demonstrated in coronary artery disease patients that DCA activates PDH, optimizes myocardial metabolic efficiency, reduces arterial lactate levels, and enhances cardiac work efficiency via increased stroke volume and decreased systemic vascular resistance (70)

Fernandes Gomes B, Kumar A, Ashton NJ et al (2024) Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders

Importantly, this outcome was demonstrated both in the overall patient population and in the approximately two thirds of patients that had SSc-ILD patients with SSc-ILD in the placebo arm demonstrated a reduction of FVC by 257 mls, while patients with SSc-ILD in the tocilizumab arm demonstrated a reduction of only 20 mls