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Se sabe que las especies de los siguientes gneros son conocidas por sintetizar la vitamina B 12 : acetobacterium, enterobacter, agrobacterium, alicaligenes, azotobacter, bacillus, clostridium, corynebacterium, flavobacterium, lactobacillus, micromonospora, mycobacterium, nocardia, propionibacterium, protaminobacter, proteus, pseudomonas, rhizobium, salmonella, serratia, streptomyces, streptococcus y xanthomonas

Carotene radicals are also prone to molecular-oxygen addition and subsequent reaction with another carotene molecule, producing carotene epoxides and carbonylated carotene compounds

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Additional pathways, including TLR-mediated signaling, MAPK pathways, and mTOR signaling, further modulate this priming stage (63, 64)