erastin cancer glutathione

erastin cancer glutathione Erastin, a ferroptosis-inducing agent, sensitized cells to X-ray irradiation via starvation in vitro and in vivo Imidazole Ketone Erastin Induces Ferroptosis

Name: erastin cancer glutathione Erastin, a ferroptosis-inducing agent, sensitized cells to X-ray irradiation via starvation in vitro and in vivo Imidazole Ketone Erastin Induces Ferroptosis
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Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model ScienceDirect The ferroptosis inducer erastin irreversibly inhibits system xc and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells Scientific Reports Mechanisms of Cell Death Induced by Erastin in Human Ovarian Tumor Cells Cell death is triggered by erastin and related compounds in different Download Scientific Diagram

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Emerging evidence further indicates that MTs particularly MT1 and MT2A constitute a critical cytoplasmic defense layer against cuproptosis by acting as effective copper sponges that sequester excess Cu + and restrict its aberrant interaction with mitochondrial targets 170,173,174