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Circulating levels of sirtuin 4, a potential marker of oxidative metabolism, related to coronary artery disease in obese patients suffering from NAFLD, with normal or slightly increased liver enzymes

Metabolism & aging (preclinical): NAD+-dependent sirtuin and PARP activity has been linked to DNA repair and metabolic regulation in animal models [11]

4 Ferroptosis in neurodegenerative diseases: mechanistic insights Ferroptosis is a regulated form of cell death driven by iron-dependent lipid peroxidation, and mounting evidence suggests its involvement in the pathogenesis of neurodegenerative diseases, including ischemic stroke, PD, AD, and HD (127)