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Your brain will compensate by reducing normal dopamine delivery over time, however, and this sets in motion a vicious cycle with you craving nicotine just to be able to feel "normal." How Withdrawal Symptoms Develop Timeline of nicotine and symptoms of withdrawal, and how acupuncture may be beneficial at each stage As soon as you stop smoking, withdrawal symptoms run their relatively typical course: Days 1-3: Strong desires to eat, irritability, Week 1-4: Fluctuating moods, depression, disturbances of sleep Months 1-3: Random urges, mood swings, sensitivity to stress Nicotine withdrawal symptoms and how acupuncture relieves them in the long run