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The DMF is considered as a prodrug, after oral administration, rapidly hydrolyzed by esterases in the small intestine and converted to MMF representing an intermediate of tricarboxylic acid cycle (TCA) (7)

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In the D1 to M6 cohort, 7 and 17 out of 25 pediatric patients achieved a complete and overall response, respectively, at 6 months

PAE is an increasingly used treatment option for the management of lower urinary tract symptoms associated with prostate enlargement (BPH)