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However, GHRH cannot be the sole mediator of ghrelins actions as the GH response to ghrelin is greater than that to GHRH (360), and, as noted above, ghrelin synergistically potentiates GH release by a maximal dose of GHRH (110)

Leung CK, Hasegawa K, Wang Y, Deonarine A, Tang L, Miwa J, Choe KP: A direct interaction between the WD40 repeat protein WDR-23 and SKN-1/Nrf inhibits binding to target DNA