Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP peg3 182 SMILES [2H]C([2H])([2H])OC1=C(C(C)=CC=C1)N(=O)=O Purity (HPLC)
Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP peg3 182 SMILES [2H]C([2H])([2H])OC1=C(C(C)=CC=C1)N(=O)=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP
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