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238 Compared with tumor-bearing rats, creatine intake diminishes plasma TNF- and IL-6 levels and alleviates splenic morphological alterations, such as reduced white pulp and lymph follicle sizes, indicating that creatine may prevent skeletal muscle atrophy by modulating the tumor-induced proinflammatory milieu

The current study showed that LCn improved sperm quality, which was in line with earlier research on LC showing that LC regulates Sertoli cell functions and significantly boosts the release of pyruvate and lactate, which are necessary for energy production and sperm cell development in the testis.[] The improvement of sperm quality by LCn in this part of the experiment is consistent with the antioxidant action of LCn and its beneficial effect on sex hormones demonstrated in this study

More recent work shows that P

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