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Furthermore, expression of AKT-E17K also increased compensatory glycolysis, the additional glycolytic activation after electron transport chain (ETC) inhibition, highlighting the importance of glycolytic activity upon IR treatment ( Figures S3AC )

doi: 10.1002/pld3.437 70

2 Mechanisms of lipedema disease progression Lipedema is a chronic disorder of the loose connective tissue characterized by pathological expansion of subcutaneous adipose tissue