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50 However, genetic and iatrogenic variations alone may not be to blame, as other comorbidities such as thyroid disease, which amplify mitochondrial or metabolic vulnerability, may increase the risk of statin-associated liver injury

References 1 New England Journal of Medicine (2023)Once-Weekly Tirzepatide for Weight Management (SURMOUNT program

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In summary, the correlation between the M1 to M2 ratio and survival outcomes and the underlying signaling pathway involved were examined by using in vitro, in vivo, and ex vivo approaches in this study