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doi:10.1089/acm.2005.11.909

How Tesofensine Works: Mechanism of Action Tesofensine is a triple monoamine reuptake inhibitor (MRI) a rare class of compounds that simultaneously boosts the availability of three key neurotransmitters: dopamine , norepinephrine , and serotonin

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The aldehyde products generated from hydroxyl radical action on PUFA are normally neutralized by glutathione conjugation or via aldehyde dehydrogenase activity in mitochondria