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Interestingly, when 5-amino-1MQ was applied to HEK-293 cells, another widely used cell line in research derived from human embryonic kidney cells, there was no significant impact on their growth

Yu X, Long YC (2016) Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis

The use of such an ROS-responsive nanoplatform for drug formulation modification may provide a new strategy for not only the delivery of deucravacitinib but also other small-molecule drugs in the JAK family, which can offer a promising clinical translation strategy