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Systematic review of human and animal studies examining the efficacy and safety of N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) in traumatic brain injury: impact on neurofunctional outcome and biomarkers of oxidative stress and inflammation

1 Introduction Gastroesophageal reflux disease (GERD) is a chronic condition characterized by reflux of gastric contents into the esophagus, which can cause uncomfortable symptoms and potential complications ( Therapeutic aspects of the combined use of probiotics have a positive effect on GERD

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Nonetheless, to evaluate the anti-aging effects of compounds, in vitro assays also measure their impact on collagenase (collagen structure), elastase (elasticity), tyrosinase (pigmentation), and hyaluronidase (hydration) enzyme activities [1, 4, 8, 11, 12] on the grounds that inhibiting collagenase, elastase, tyrosinase, and hyaluronidase is crucial for preserving collagen and elastin integrity