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Participants who reported the presence of five or more of the nine symptoms listed on this questionnaire, with at least one symptom being: 1) loss of interest or pleasure, or 2) depressed mood, were categorized as having major depressive symptoms (MDS)

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New studies performed by Indiana University have shown that E-cigarettes apparently may not be as safe as originally thought and that the vapors put off by the E-cigarettes could also attribute to damaging side effects to the cells in the lungs