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If the maintenance dose of 2.4 mg per week is not well tolerated, temporarily reduce it to 1.7 mg per week for up to four weeks

Compared with ADCs, PDCs exhibit better tumor penetration because of their small molecular weight, lower systemic exposure (owing to rapid clearance from the body), lower risk of immunogenicity and liver damage, and easier and cheaper production methods

We're seeing more and more studies leverage this prolonged effect to understand long-term metabolic adaptations, a demanding, often moving-target objective in this field

The pharmacists there can also provide valuable advice on dosage and usage