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doi: 10.3389/fmicb.2019.01136 Received 13 September 2018 Accepted 06 May 2019 Published 10 June 2019 Volume 10 - 2019 Edited by Vishal Singh, The University of Toledo, United States Reviewed by Konstantinos Papadimitriou, Agricultural University of Athens, Greece

Future research should focus on finding a set of signaling mediators that cause the P2X7 receptor to use different signaling pathways depending on the microenvironment and the concentration of signaling ligands

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