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In addition, high protein intake also increased renal flow and GFR as compared with rats fed a low-protein diet, while decreased renal vascular resistance, actions that were associated with the higher serum IGF-1 levels.83 As previously mentioned, the glomerular hemodynamic effects of IGF-1 are mainly due to increased glomerular ultrafiltration coefficient and decreased efferent arteriolar resistance

Methylene blue neurological benefits include potentially improved cognitive performance and neuroprotection through mechanisms like increasing Nrf2 expression (how much of a protein, called Nuclear factor erythroid 2-related factor 2 (Nrf2), is being made or activated in the cells

10.1016/j.freeradbiomed.2012.07.021 Free Radic

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