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Human studies have shown that PYY delays gastric emptying and promotes satiety (165), while short-term intravenous administration of PYY3-36 , at doses generating physiologic postprandial blood excursions, was shown to decrease calorie intake by approximately 30% in lean and obese subjects, without causing nausea, affecting food palatability, or altering fluid intake, nor was it followed by compensatory hyperphagia (166)

Lastly, while we acknowledge that the service provided under HCPCS code G0465 may differ from skin substitutes, we consider the work to be comparable, which is why we are using CPT code 15275 as the crosswalk