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The extracellular citrulline autoantigen present in the joints of RA patients is mainly derived from the increased NET, which can cause the inflammatory response of synovial fibroblasts in patients and release a series of inflammatory mediators (such as pro-inflammatory cytokines, adhesion molecules and chemokines) to drive the progression of RA (205)

(III) Optimizing pharmacological treatment for COPD The most rigorous and comprehensive data available for preventing ECOPD and hospitalization is the appropriate pharmacologic treatment of COPD 45

Theoretical aspect of BPC-157 action on the nervous system Characteristics of nootropic drugs Nootropic drugs belong to a group of medications that are intended to have therapeutic effects by improving cognitive functions, such as enhancing memory or concentration and attention

A complete description of the full mathematical model and the values of all parameters are given in the online Additional File 1