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In addition, electron microscopy analysis indicated that the composite IONPs first formed a protein crown-nanocomplex during systemic circulation, and then, under the action of an external magnetic field, they successfully penetrated vascular endothelial cells and entered the brain parenchyma (Fig

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(6) Alternatively, to determine bacterial survival within MDM-NK cell co-cultures, total cells along with the culture media were collected and centrifugated at 3600 g at 4 C for 5 min