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Williams et al., 1992)

4 Chemotherapy and cell death pathways modulation Cell death, a crucial aspect of the response to chemotherapy, can occur through various mechanisms, each influencing chemoresistance: during tumor progression, the balance between pro-cell death and anti-cell death regulators is shifted towards survival by various escape mechanisms ( Apoptosis, discovered in 1972, is a programmed and controlled process of cell self-destruction requiring specific cell signaling transduction (Wang et al., 2023)

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways