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BI2536 (HY-50698), MLN8237 (HY-10971) and ZM447439 (HY-10128) were all purchased from MedChemExpress

Free Radic Res 37(2):205211 Lo TW, Westwood ME, McLellan AC et al (1994) Binding and modification of proteins by methylglyoxal under physiological conditions

G6PD serves an important role in nucleic acid synthesis via generation of ribose 5-phosphate, and in the cellular response to oxidative stress through the generation of reduced nicotinamide adenine-dinucleotide phosphate (NADPH) (1,2)

Type 1 IGF receptor-immunoreactive cells were counted in the GCL and INL of the rats in all three groups in order to determine if the changes in immunoreactivity were significant