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The circRNA that recorded the highest level of upregulation in that study, hsa_circ_0008367, has great potential as a biomarker of ferroptosis induced by SF

Bioinformatics 26 (6), 715721 (2010)

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One study conducted high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy on degenerated adult human lumbar discs and demonstrated a correlation between changing metabolite concentrations and degrees of degeneration (Radek et al., 2016)