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In addition to impairing insulin signaling, adipocyte derived FAs can also impact gluconeogenesis in the liver, where a hallmark of T2D is the loss of the inverse relationship between gluconeogenesis and lipogenesis

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Moreover, K(D)PT, a derivative of KPV, has also demonstrated potent anti-inflammatory effects, offering further research potential in the context of immune-mediated inflammatory diseases affecting the skin, bowel, eyes, and joints