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A key study investigating coagulation factors employed a two-sample Mendelian randomization (MR) approach using large-scale genome-wide association study (GWAS) summary statistics from the UK Biobank (4354 cases, 217,500 controls) and FinnGen (8288 cases, 68,969 controls) cohorts to explore causal associations between 11 coagulation factors and endometriosis risk

Integrated analysis of multi-omics data: integration of metagenomic sequencing technology, untargeted metabolomics analysis, and detailed clinical phenotype data should construct systems biology network models of microecology-metabolite-disease interactions (162)

For instance, by using ph-sensitive or temperature-sensitive materials, drugs can be released under specific conditions, thereby enhancing the therapeutic effect

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