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518 Furthermore, increasing the level of available NAD + by supplementing diet containing NAD + precursors or inhibiting the activity of NAD + -dependent enzyme (e.g., PARP that snatches NAD + competing with mitochondria) is a feasible strategy to avoid the neurotoxicity related to mitochondrial dysfunction

Comprehensive Physiology , 4 (1), p.177

The goal is to study ways to work with the bodys repair systems, but on an accelerated timeline

Adv Drug Deliv Rev 63:10531073 Ohtake S, Martin R, Saxena A, Pham B, Chiueh G, Osorio M, Kopecko D, Xu D, Lechuga-Ballesteros D, Truong-Le V (2011) Room temperature stabilization of oral, live attenuated Salmonella enterica serovar Typhi-vectored vaccines