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Diagnosis involves serum B12 measurement, full blood count, and investigation for underlying causes including intrinsic factor antibodies for pernicious anaemia

One exception is when the bladder has so much blood in it that clots form, and the flow of urine is blocked

Common signs and symptoms include Skin reactions, including hives and itching and flushed or pale skin Wheezing and breathing trouble Slurred speech Shock Nausea, vomiting or diarrhea Low blood pressure (hypotension) Facial swelling Dizziness or fainting Difficulty swallowing Constriction of airways and a swollen tongue or throat Anxiety and confusion Abdominal pain A weak and rapid pulse There are not many known risk factors for anaphylaxis, but certain things may increase the potential risk associated with the condition and these include previous anaphylaxis, allergies or asthma and certain other conditions (like heart disease and an abnormal accumulation of a certain type of white blood cell (mastocytosis)