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It is yet unclear how ferroptosis and other cell death mechanisms interact, and research is needed to understand their cross-regulatory networks utilizing genetic engineering models like GPX4/ACSL4 double knockout systems

10.1534/genetics.119.302939 27 IzadiA.EbrahimiS.ShiraziS.TaghizadehS.ParizadM.FarzadiL.et al (2019)

Dermatology 152 , 13041312 (2005)

Only by bridging laboratory research with evidence-based medicine can we fully harness the potential of these active components in suppressing glucolipotoxicity and reducing the risk of diabetic complications