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Description

PARP inhibitors , including olaparib and niraparib , impair DNA repair in BRCA-mutated cells and are approved for ovarian, breast, pancreatic, and prostate cancers

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Their study revealed that hepatocyte glucose output decreased by 50% with NNMT knockdown, while NNMT overexpression increased it by 1.4-fold

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and the activities are continuing in FY 2013/14

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