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Several natural compounds have been proposed as interventions for PD including coenzyme Q10, curcumin, resveratrol and omega-3 fatty acids, however these agents have shown limited clinical efficacy, often failing to produce measurable changes in Unified Parkinsons Disease Rating Scale (UPDRS) outcomes or biomarkers of oxidative stress

3) ( with disulfides is relatively slow in solution, the protein environment and the presence of a better leaving group in trisulfides (a second persulfide, Eq

For qRT-PCR, primers were designed using the Primer3 platform ( (Supplementary Table S3) and their efficiencies (ranging from 90 to 110%) were validated by a standard curve with five 5 serial dilutions of the antennal cDNA of G