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In the body, it regulates metabolism in the epiphysis, increases the sensitivity of the hypothalamus to its natural hormonal influences, and normalizes the function of the anterior pituitary, including its regulation of gonadotropins and melatonin

Lipid Profile Tirzepatide was associated with dose-dependent favourable effects on lipid profile, including reductions in triglycerides and very-low-density lipoprotein cholesterol (VLDL-C), and increases in high-density lipoprotein cholesterol (HDL-C) in SURPASS-15 [8,9,10,11,12]

In the TRIUMPH-1 trial, the 4 mg dose had a lower discontinuation rate due to adverse events than even placebo, suggesting that lower doses are well-tolerated

Zhang R, Zhang Q, Zhu S, Liu B, Liu F, Xu Y (2022) Mulberry leaf (Morus alba L.): a review of its potential influences in mechanisms of action on metabolic diseases